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Patients should seek medical attention if they experience severe or persistent gastrointestinal symptoms, signs of pancreatitis (severe abdominal pain radiating to the back), symptoms of thyroid tumors (neck mass, difficulty swallowing, persistent hoarseness), right upper quadrant pain, jaundice, reduced urine output, or unexplained hypoglycemia

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1c) of acid-ethanol extracts of rat gastric and ileal mucosa identified proglucagon, GLP-1, and GLP-2 fragments consistent with PC1/3 cleavage sites after trypsin, Lys-C, chymotrypsin, and Glu-C digestion

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Liraglutide and semaglutide have similar side effect profiles, it appears to be a class effect

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