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PMID 18787098
It is majorly based on the restriction of RNS and ROS formation and neutralization of free radicals
doi:10.1042/bse0340139
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discovered that lactate, produced through glycolysis in pancreatic ductal adenocarcinoma (PDAC), can promote H3K18la under the catalysis of P300, thereby enhancing the transcription of mitotic checkpoint regulatory factors TTK and BUB1B
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