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Current indirect evidence from the cardiovascular outcomes trials suggests that cardiovascular benefits are at least partly independent of glucose-lowering, but the same analysis was not done for weight loss. They also want to examine oral semaglutide separately from the subcutaneous formulation, particularly now that an oral version has been approved for weight loss, and to consider dose effects
#MASH #Hepatology #GLP1 #PharmaInsights To view or add a comment, sign in #MoleculeMonday: Thalidomide was once a global tragedy
This central effect is a key reason why GLP-1 agonists are so effective for weight loss
The LDSC analysis indicated a significant association (rg = 0.36, P = 3.40 10 46 ) between T2D and SA
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