mounjaro tirzepatide news today september 2025 Massively disappointing from @elilillyco on a muscle preserving weight loss combo. #tirzepatide #zepbound #mounjaro #bimagrumab ⚠️Medicine shortage update - Discontinuation

It's best to swallow the capsule whole and avoid crushing, chewing, or breaking it

GLP-1 drugs which include Ozempic and its sister drug Wegovy, as well as Mounjaro and Zepbound mimic at least one hormone produced by the gut to signal fullness, leading to a reduced appetite

The goal is to quiet things down for the next meal or next day, not to overhaul your entire life from your kitchen counter

Across SELECT, STEPlike trials, pediatric obesity studies, and ESSENCE, Wegovy demonstrates robust, durable weight loss, clinically meaningful CV risk reduction, and promising liver histologic responses, albeit with an established GIdominant tolerability profile and specific but manageable safety concerns

D., Najafi, A., Nguyen, J., Seay, M

Any additional urinary effects would come from tirzepatide typically producing greater weight loss, which means slightly more glycogen depletion and water release