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By blocking NNMT, 5-Amino-1MQ prevents NAD+ breakdown , allowing its levels to rise

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Efficacy-wise, AOD-9604 produces modest results (2-3 kg over 12 weeks in trials) compared to GLP-1 agonists dramatic weight loss

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It is a single small aromatic molecule designed to be membrane-permeable, so in principle it can survive the gut and cross into cells

5-Amino-1MQ for Muscle Regeneration Studies suggest that inhibiting NNMT and increasing levels of NAD+ may promote muscle regeneration in various models, including aging skeletal muscles, muscle injury, and cardiac muscle dysfunction [6]: One study investigated the potential benefits of 5-amino-1MQ on muscle regeneration in aging