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Drug Saf (2008) 31:5365
Higher concentrations aren't necessarily better and can increase the risk of irritation
Small molecule programs remain high risk high reward Pfizers pullback from its own oral GLP-1 programs has highlighted a major scientific challenge: biased agonism can improve GI tolerability but does not eliminate hepatotoxicity risk
These routines not only support long-term weight management but also contribute to overall health
doi: 10.3390/nu10111637 120 Seyyed AbootorabiMAyremlouPBehroozi-LakTNourisaeidlouS
![Physiologic effects of GLP-1 (adapted from Granata et al. [11])](https://www.researchgate.net/publication/359199250/figure/fig1/AS:11431281081130351@1661532031197/Physiologic-effects-of-GLP-1-adapted-from-Granata-et-al-11.png)
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