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The threshold increase is precautionary

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This is because NNMTi improves fat metabolism to assist weight loss, alleviates intestinal inflammation, and reduces gastrointestinal adverse reactions.These combined intervention studies provide novel strategies for clinical obesity management and expand the application scope of NNMTi

They include all of the following perks

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Before human translation, essential parameters to define: optimal dosing, infusion/administration route, frequency, biomarkers to monitor (senescent cell burden, inflammatory cytokines, organ function), long-term follow-up for adverse outcomes (especially tumour risk)