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Modest, at roughly 5 to 10 percent of body weight in responders over 56 weeks, achieved through central nervous system modulation rather than slowed gastric emptying or incretin stimulation
Use your new weight in the BMR formula, then apply the same activity multiplier and deficit calculation
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10.1016/j.jhep.2017.11.014 50
doi:10.1210/jc.2004-1719 Berlanga-Acosta J, Abreu-Cruz A, Herrera DGB, et al
The more modest increases from 4mg to 8mg to 12mg suggest diminishing returns once the glucagon threshold is crossed
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