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Epub 2019 Nov 29
Semaglutide, with its 7-day half-life, maintains therapeutic plasma concentrations continuously, producing consistent 24-hour receptor activation and clinically meaningful metabolic improvements
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Stimulation of these receptors, expressed in a wide range of tissues, including the pancreas, liver, gastrointestinal tract, kidneys, heart, endothelium, muscles, and brain, mediate multiple effects on the body