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In the ARC, activation of the JAK2/STAT3 pathway by leptin inhibits the activity of neurons expressing NPY and AgRP, which are orexigenic (appetite-stimulating)
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Early intervention is key to preventing long-term complications
Glucagon-like peptide-1 therapy and the exocrine pancreas: innocent bystander or friendly fire
Structural and functional reorganization of propriospinal connections promotes functional recovery after spinal cord injury
If a GLP-1 is available and appropriate, it can be an effective option to try prior to surgery. Other times, GLP-1s are recommended for people with extremely elevated BMIs to help them lose weight in preparation for weight loss to surgery, which can lead to a safer surgery
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