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This document is for health care professionals who will be diagnosing and prescribing vitamin B12 in adults in primary care across NHS South West London
Scientists first discovered how B12 works in the 1950s
BPC-157 supports this interconnected system by: Strengthening tight junctions between intestinal epithelial cells, reducing intestinal permeability (leaky gut) Modulating the enteric nervous system to normalize motility and reduce visceral hypersensitivity Regulating mucosal immune responses to prevent inappropriate inflammation against dietary and microbial antigens Conditions Treated with Oral BPC-157 Beyond Symptom Relief: Addressing Root Causes Unlike proton pump inhibitors (PPIs) that suppress stomach acid or corticosteroids that broadly dampen immunity, BPC-157 works by restoring the underlying structural and functional integrity of the gastrointestinal tract
This difference was achieved without any change in food intake, suggesting the weight loss came from metabolic changes rather than appetite suppression
Cycling advantages include reduced annual costs through intermittent purchasing (30-40% savings vs continuous use), potentially improved responsiveness when restarting after breaks avoiding adaptation, psychological freedom from continuous dependency, and accommodation of life changes, travel, or budget fluctuations
Additionally, some studies suggest that iron deficiency can inhibit the conversion of T4 to the active T3 thyroid hormone
