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Current evidence from randomised controlled trials, meta-analyses, and real-world studies indicates no consistent or causal relationship between these agents and serious GI side effects
Zhao, M., Kim, P., Mitra, R., Zhao, J
O'Brien, 2005
This process is governed by a conserved and finely regulated enzymatic pathway involving Branched-Chain Aminotransferase 4 (BCAT4), Methylthioalkylmalate Synthase 1 (MAM1), and Cytochrome P450 Monooxygenase CYP79F1, with master transcriptional regulators like MYB28 orchestrating the overall flux (912)
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