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GLP-1R agonists may improve the function of the gut-brain axis and stability of the gut microbiota Many recent reports also emphasize the role of the gut-brain axis and stability of the gut microbiota in the development of mood disorders, including depression
distinguishing these from Wegovy's common side effects requires noting the prominent psychological features, such as fear of dying or losing control
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Worsening of diabetic retinopathy: Rapid improvement in blood glucose control has been associated with transient worsening of diabetic retinopathy in people with pre-existing retinopathy
Mechanistic studies indicate that GLP-1RAs suppress the perception of all basic taste modalities, probably through combined actions in the brainstem and vagal modulation, although paradoxical cases of sweet hypersensitivity have been documented in specific populations (162)
Lancet 377 , 977979 (2011)
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