Semaglutide significantly reduces caloric intake by increasing feelings of fullness and decreasing hunger, leading to substantial weight loss in clinical trials
Zenobi PD, Glatz Y, Keller A, Graf S, Jaeggi-Groisman SE, Riesen WF, Schoenle EJ, Froesch ER
They can hinder weight loss efforts and cause blood sugar spikes
This is known as the plateau, and it can happen when you lose too much muscle and fat simultaneously
Here are the main concerns: Interference with Fetal Development Since tirzepatide affects blood sugar levels and other metabolic processes, there is a possibility that it could interfere with the normal development of the fetus
Notably, orforglipron exhibited the highest risk, followed by exenatide, tirzepatide, semaglutide, and liraglutide