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Whenever possible, we determined the rate constants for the interconversion between the different oxidation states of TGR by kinetic methods
CR can significantly reduce the activity of mTOR and downstream S6K, thereby delaying cellular senescence and prolonging the life span of mice (Schloesser et al., 2015)
It is classified as a triple incretin receptor agonist, meaning it simultaneously targets three hormone receptors: glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP), and glucagon receptors
Ren B, Huang W, Akesson B, Ladenstein R (1997) The crystal structure of seleno-glutathione peroxidase from human plasma at 2.9 A resolution
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