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- when there is risk of torsades de pointes, for example in patients with prolonged QT, concomitant administration of other medications that produce torsades de pointes (amiodarone, quinidine, bepridil, IV erythromycin, halofrantine, pentamidine, sparfloxacin, sultopride, vincamine, betrilio, disopyramide, sotalol, etc)

B complex deficiency is normally caused due to four possible reasons

Once the deficiency is addressed, a maintenance dose can be given to keep B12 levels within the optimal range

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Quality, dosing, safety, and medical supervision matter

The blend is therefore commonly explored in preclinical models focused on tissue repair, inflammation modulation, and cellular recovery processes