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Concomitant medications : Review and, if necessary, adjust doses of other glucose-lowering agents (e.g., sulfonylureas, insulin) to reduce hypoglycaemia risk

This dual receptor action allows Tirzepatide to enhance insulin secretion, suppress glucagon release, slow digestion, and boost satiety similarly to semaglutide, but with the added benefit of activating the GIP receptor

When medication integrity is compromised by heat, these genetic factors become even more relevantyour provider may adjust dosing, frequency, or medication choice based on both genetic context and observed treatment response

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