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Advise patients to report symptoms of severe and persistent eye pain or significant vision changes to their clinician

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Although lean mass was reduced in myocyte-ARKO males, this was independent of changes to bone parameters as myocyte-ARKO did not affect trabecular or cortical bone outcomes measured by micro-CT

These facial changes occur due to multiple physiological factors, including: Loss of facial fat compartments that provide structural support Accelerated breakdown of collagen in the skin Reduction in elastin fibers that maintain skin elasticity Depletion of essential nutrients including fatty acids Most concerning is that these changes often develop gradually and may not be fully noticed until theyve become significant

CagriSema combines amylin and GLP-1 agonism