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Long-term risks of Trulicity include the potential worsening of or new onset kidney damage and severe digestive problems such as gastroparesis or ileus

Risk Summary Based on animal reproduction studies, there may be potential risks to the fetus from exposure to semaglutide during pregnancy

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The Harmony Outcomes post-hoc analysis also showed a similar trend with respect to MACE and HHF, although kidney outcomes were not examined (Table 3) [48]

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The capsule formulation offers researchers advantages over powder form including reduced exposure risk, better handling characteristics and more consistent experimental parameters