W., Yang, X
In addition, the direct photolysis reaction is also considered in the excited state to reveal the mechanism of the photochemical reaction
On 5-on/2-off it is 10 doses = 1,000 mcg (1.0 mg)
Reviewed by the PeptideMind Team Updated July 28, 2026 Melanotan 1 vs Melanotan 2: Key differences comparison The main difference between Melanotan I and Melanotan II is selectivity: Melanotan I targets one receptor and builds pigment only, while Melanotan II targets several, which is also why it's linked to appetite and libido effects
Its MC1R selectivity is what separates it pharmacologically from the broader, multi-receptor Melanotan II [3]
Both contain the same active ingredient and share similar pharmacokinetics, indications, efficacy, and safety profiles, yet they are prescribed for different conditions