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Liraglutide (Victoza)

Two compounds each supported only by rodent studies do not, when mixed in a vial, produce a therapy supported by human data

Findings In total, 99 individuals were recruited and invited to complete the three-day food record

The compounds work differently enough that direct dose translation is not valid

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16.1% on semaglutide Tirzepatide was superior on all five key secondary endpoints Gastrointestinal discontinuation rate was lower with tirzepatide (2.7%) than semaglutide (5.6%) These findings were consistent across all patient subgroups, regardless of sex, age, baseline BMI, or presence of metabolic comorbidities