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Treatment of Adult Obstructive Sleep Apnea With Positive Airway Pressure: An American Academy of Sleep Medicine Systematic Review, Meta-Analysis, and GRADE Assessment

After an application by plaintiffs to organize the case in a Multidistrict Litigation (MDL), the two largest defendants, Novo Nordisk and Eli Lilly, are split on their response to the application

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REDEFINE 1 enrolled 3,400 adults with obesity but no diabetes

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However, the precise molecular cascades linking MC4R activation to behavioral outcomes remain incompletely characterized