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Fatigue Reduction: A 2023 systematic review found that while not everyone responds, roughly 40% of patients with advanced cancer reported a noticeable improvement in their daily energy levels within 4 weeks of starting 4g daily doses
Drugs.com (2025) 10
This gradual titration is specifically designed to minimize gastrointestinal side effects, which are the most common reason for discontinuation
Kannt, A., et al
245 ProcacciniCLa RoccaCCarboneFDe RosaVGalganiMMatareseG
Paladugu L, Gharaibeh A, Kolli N, Learman C, Hall TC, Li L, et al
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