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doi:10.1073/pnas.89.18.8641
PMID: 36629465
The primary outcome studied across all the trials was the first occurrence of death from cardiovascular causes, nonfatal myocardial infarction, or nonfatal stroke
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While these findings suggest potential utility for early detection and risk stratification, multicenter validation and longitudinal follow-up are needed to confirm that alterations in carnitine levels precede eGFR decline and are not merely a consequence of impaired renal clearance
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