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Limitations of Current Evidence Several critical limitations characterize the current evidence base for these peptide therapeutics
The effects of BPC-157 on HUVECs might be mediated by activation of ERK1/2 phosphorylation, leading to enhanced cell proliferation, migration, and tube formation
doi:10.1093/ajcn/74.2.233
The peptide multiple mechanisms of action, including angiogenesis, collagen synthesis, and anti-inflammation, all contribute to accelerated healing of these tissue types
No human study shows that SubQ BPC-157 builds new capillaries in skin or improves a KLOW outcome
PLoS ONE 7 , e45518 (2012)
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