The N-terminus of the amylin peptide is predicted to form a loop, stabilized by a disulfide bond, that points out of the TM area, thereby tolerating N-terminal lipidation
Suitable for studies involving peptide characterization and method development in model systems.Not for human use
Furthermore, the overexpression of -syn disrupts the interaction between mitochondria and the endoplasmic reticulum, interfering with Ca 2+ homeostasis and further inducing defects in mitochondrial fission (Tassone et al., 2023)
Allelism of MCKD, FJHN and GCKD caused by impairment of uromodulin export dynamics
1 Although menopause is a normal life stage and not a disease, it is associated with increased risks of chronic cardiovascular, metabolic, neurological, and musculoskeletal disorders
Gut physiology and environment explain variations in human gut microbiome composition and metabolism