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In preclinical models it has been associated with cytoprotection , modulation of nitric-oxide pathways and angiogenesis , with reported activity across gastrointestinal, musculoskeletal and other tissues [1] [2]

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Variants in FTO (the fat-mass and obesity-associated gene), GLP1R (the GLP-1 receptor gene that every GLP-1 compound targets), MC4R (a melanocortin receptor central to satiety), and TCF7L2 (a transcription factor tied to glucose control and GLP-1 secretion) describe your baseline metabolic biology

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