Akkermansia muciniphila secretes a glucagon-like peptide-1-inducing protein that improves glucose homeostasis and ameliorates metabolic disease in mice Nature Microbiology 2021;6(5):563-573 doi:10.1038/s41564-021-00880-5 Tolhurst G, Heffron H, Lam YS, et al
Also, CKD causes inflammation and endothelial dysfunction which promotes remodeling
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Further, genetically predicted lower BMI was associated with reduced risks of MDD, BD, and BD I after correction for multiple comparisons, while associations with SUDs, postpartum depression, ADHD, and BD II were suggestive