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Both oral semaglutide and injectable GLP-1 medications work through the same biological pathway, but they differ in delivery, convenience, and administration details: 1
Kaklamanos et al., 2021
Standard $299399/mo Full Dosing Protocol Standard semaglutide dosing with DEXA tracking, physician monitoring, and dose adjustments
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The extended-release (ER) formulation encapsulates exenatide within biodegradable poly(D, L-lactide-co-glycolide) (PLGA) microspheres, which form a polymeric matrix that allows sustained drug release following SC administration [13, 14, 58]
TL;DR Zepbound (tirzepatide) is an FDA-approved injectable medication that works by activating two hormone receptors-GLP-1 and GIP-simultaneously, making it the first dual-agonist weight loss drug
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