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Research uses MT-1 to study whether the anti-inflammatory and melanogenic arms of MC1R biology can be pharmacologically dissected through downstream pathway selective interventions examining whether PKA inhibition differentially affects the two outputs and contributing to understanding of how MC1R-cAMP signalling branches to produce distinct cellular outcomes simultaneously

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Inhibition of DPP-4 reduces acute mortality after myocardial infarction with restoration of autophagic response in type 2 diabetic rats