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Tirzepatide stimulates insulin secretion through the GIPR in human islets from healthy donors, supporting a role for GIPR agonism in its pharmacology (56)

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4.9%), compared with the placebo group

However, upon release in the hydrophilic cytoplasm, the fluorescence of the dye is quenched, allowing for the facile detection of the degradation of the nanoparticles

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