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All of the compounds above have been proven to maintain GSH contents and GSH-dependent antioxidant enzyme activities in the myocardium, protecting it from oxidative stress [41, 158,159,160,161,162,163,164]
Hence, the number of ATP is reduced in every reaction, synthesis of -GC can act as a rate-limiting factor for GSH synthesis, and the -ECS activity depends on Cys-availability
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McConnachie, L
Research has revealed a unique protease activation phenomenon in MELAS: LONP1 exhibits subcellular compartmentalized aggregation in primary cells from patients with MELAS, with its protein abundance particularly elevated in cell populations enriched with mutant mtDNA
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