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Published 2024.
Sincerely appreciative of the team and leadership that made this possible
Gut 59 (2), 227235
Very recent study found significant improvement of behavioral deficits including cognitive decline, depressive-like behaviors, in APP (NLG-F/NLG-FG-) mice due to oral GSH administration
This process is governed by a conserved and finely regulated enzymatic pathway involving Branched-Chain Aminotransferase 4 (BCAT4), Methylthioalkylmalate Synthase 1 (MAM1), and Cytochrome P450 Monooxygenase CYP79F1, with master transcriptional regulators like MYB28 orchestrating the overall flux (912)
This makes it particularly effective for individuals who report feeling mentally disconnected from desire, even when physical function is intact
