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Molecules 29(1):136 Rotruck JT, Pope AL, Ganther HE, Swanson AB, Hafeman DG, Hoekstra W (1973) Selenium: biochemical role as a component of glutathione peroxidase

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Acquired deficiencies due to liver disease or vitamin K deficiency also impair clotting cascade proteins and increase bleeding tendency

Ethics declarations Ethics approval and consent to participate The animal protocol employed in this study was approved by the Animal Experimentation Committee of Jinan University (IACUC-20191212-02)

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