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Both Melanotan products work by increasing the levels of melanin, a natural dark pigment that provides some protection from the sun
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However, combining GLP-1 to estrogen delivers additional efficacy relative to GLP-1 alone on insulin sensitivity and glucose homeostasis in non-diabetic mice
This approach allows any initial side effects to peak during the weekend when they have more flexibility to rest and hydrate at home
However, it remains an investigational medicine , and more evidence is needed before it can be approved and prescribed in the UK
2024 Feb 1;184(2):144-152
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