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It's fundamental biology documented across decades of research
For instance, estrogen exposure can downregulate HDACs and upregulate the methyltransferase EZH2, thereby altering chromatin compaction and gene silencing [187]
PMC Chang CH, et al
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We classified human lung macrophages into four distinct subsets: (1) a proliferative subset marked by the expression of MKI67, (2) PPARG macrophages, (3) Monocytic macrophages expressing CD14 and IL1, and (4) C1Q macrophages (Fig
10.1155/2019/9613090 104 NitaM.GrzybowskiA
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