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In mammals, this subclass is comprised of four main members: FOXO1, FOXO3, FOXO4, and FOXO6 (Santos Bruno et al., 2023)

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Pt II -08 and Pt II -09 were moderately cytotoxic and selective after 24 h of incubation with the cells, especially against MCF-7, SW-620, and MCF-10A

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