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These may include nausea, bloating, or diarrhoea

We searched for publications in the PubMed, Web of Science, and Embase databases.The search was performed using the Medical Subject Headings (MeSH) terms for ketogenic diets (KD), -hydroxybutyrate (BHB), and ketone body in conjunction with the MeSH terms for diabetic kidney disease(DKD), diabetes and kidney

It is often described as a triple-agonist due to its activity on GLP-1, GIP, and glucagon receptors

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However, women may experience stronger appetite suppression effects and may benefit from slower titration in some cases

Information based on Ro.co's January 5, 2026 announcement, Novo Nordisk public statements, and FDA regulatory information available at time of publication