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Supplementary Figure 1
C3 is a downstream product of the metabolism of branched-chain amino-acids (leucine, isoleucine, valine) and of odd-chain fatty acids
Peptides 77 , 2837 (2016)
Hydration and fueling also matter
Compounded sublingual drops have become increasingly popular as an alternative to injections
Use of SGLT2 inhibitors was low in STEP-HFpEF, as patients with diabetes were excluded, and these agents were not yet approved for treatment of HFpEF during the trial conduct
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