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Heterologous expression of OATP2B1 produces a Na + -independent, pH-gradient dependent transporter with a relatively narrow substrate specificity compared to other OATPs (Nozawa et al

Using the mechanism, NMPA expects manufacturers to assess the MAHs qualifications, quality management capabilities, the risk factors of the proposed products, and the feasibility of accepting technical transfer and of co-line production

All mice were euthanized on day 15

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Avoid repeated environmental exposure Handle carefully during use and storage Follow batch-specific guidance where provided Inspect packing integrity before use Careful handling supports product consistency and minimizes risk of contamination

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