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In patients with cutaneous T-cell lymphoma receiving bexarotene therapy (synthetic retinoid), blood TSH levels and free T4 have been found to decline ( 2 daily) ( 2 ) or placebo, plasma TSH levels decreased as early as 12 h after therapy and reached a nadir at 24 h
Symptoms may be more noticeable during treatment initiation or dose escalation
A pen exposed to heat or light may degrade and cause more irritation
More research is needed first
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