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The Lancet (2021) 5
30 March 2020
Quick Answer: GLP-1 agonists show preliminary promise for binge eating disorder but lack FDA approval and robust clinical trial evidence for this indication
Yet, research suggests that GLP-1 secretion from the gut may be modestly reduced in people living with obesity, which can interfere with the hormones ability to signal fullness effectively
To ensure that these results were not impacted by a differential influence of the different knockdowns on cell viability, we monitored the silenced cells for compromised health using the nucleic acid dye SYTOX, which cannot cross the plasma membrane of healthy cells
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