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Conclusions Evidence accrued so far suggest that GLP-1RA could exert a modest renal benefit alongside CV protection, justifying its place as second-line drug in patients with T2D and CKD not achieving glycemic control with SGLT-2i and metformin according to KDIGO guidelines [87]

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[1] [3] This distinguishes semaglutide from some medications that may contribute to dry mouth, such as SGLT2 inhibitors (which can cause dehydration through increased urination) or anticholinergic medications (which directly reduce salivary flow)

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These are not semaglutide side effects and should prompt evaluation