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Muscle Repair 8/10 How a damaged muscle closes a defect and restores structure or function in injury models
Present in virtually every cell, glutathione plays indispensable roles in detoxification pathways, immune system regulation, DNA synthesis and repair, protein synthesis, and enzyme activation throughout the body
For example, ginger-derived miRNAs, absorbed through the gut, can reshape the gutbrain axis by altering gut microbiota composition and regulating intestinal immune responsesan indirect regulatory route increasingly recognized as a critical link to neurodegenerative progression [250, 251]
Consistent with the ion-centric model above, HIV-1 Tat can upregulate NLRP3, promote ASC oligomerization and caspase-1 activation, and augment IL-1 release by inhibiting miR-223, thereby contributing to microglial activation [101] (Fig