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Additionally, these treatments significantly decreased the level of MDA in hepatic tissue when compared to the group treated with MTX alone

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The protective effect of UA in parkinsonian model systems is also found to be dependent on Glut9-mediated transport, which is upregulated by UA in dopaminergic neurons in vitro 38

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This effector contains a ChaC-like domain and exhibits GCT activity, thereby targeting the hosts GSH-based defense system (Wei et al., 2017)