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NovoRapid (Insulin Aspart) NovoRapid sales in 2022: $2.259 billion Company/Developer: Novo Nordisk Date of first FDA approval: June 7, 2000 Indications NovoRapid is FDA-approved for: Type 1 and 2 diabetes Price of NovoRapid: NovoLog FlexPen (pre-filled NovoRapid pen) injectable solution (100 units/mL) is around $157 for 15 mL Why it did so well: Novo Nordisk joined other insulin makers, led by Eli Lilly, last year and cut the price of its insulin analog NovoRapid by 25 percent, bringing its cost down to $72.34 from $289.36

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Rather than incentivizing new medicines, patents now primarily drive the adoption of a profit-focused approach

J Diabetes Investig 13(7):11221128

The wide distribution of GLP-1R underscores the variety and significance of its biological functions