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HaCaT keratinocytes have also been proven to be good candidates for assessing skin irritancy and toxicity in conventional monolayer assays measuring using MTT reduction as the viability endpoint 21

GSEA was executed using the standard weighted enrichment statistic and 1,000 phenotype permutations to ensure robust FDR estimation

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Inhibiting key metabolic nodes such as FAO, HBP, or -KG signaling in TAMs can restore antigen presentation and enhance T-cell-mediated cytotoxicity

This helps to awaken dormant follicles, promote hair regrowth, and extend the hairs growth phase (anagen phase), leading to thicker, fuller hair over time