This case study , published in 2023, describes three female patients taking semaglutide who visited their healthcare clinic due to severe mouth dryness, as well as minimal frothy saliva. After underlying medical problems were excluded (such as low water intake or a condition called Sjogrens disease) as the cause, the females were diagnosed with hyposalivation (dry mouth)
Final concentrations of DM, D90A and K26A were 510 nM, 512.5 nM and 50100 nM, respectively
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higher doses produced transient facial flushing, headache, and dizziness
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