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I went from dragging through afternoons to feeling sharp all day. Chris M

Its plasma levels decline significantly with age (from ~200ng/mL at 20 to ~80ng/mL at 60), making it a key compound for aging biology and regenerative research

Here increased cholesterol uptake is mainly responsible for this metabolic change which is controlled by the increased SR-B1 expression caused by platinum-treatment

Its often called the master antioxidant not just because of its own antioxidant activity, but because it recycles vitamins C and E back into their active forms, amplifying the bodys broader antioxidant network

This difference may affect response patterns

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