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How do the potential benefits of GLP-1 agonists in reducing risks of heart and kidney disease compare with the risks of side effects like hypoglycemia or gallbladder disorders, and how should a clinician balance these considerations

In prostate cancer, expression of androgen receptormediated LAT3 ( SLC43A1 ) and leucine uptake can be inhibited by anti-androgen treatment, inducing the compensatory upregulation of LAT1 ( SLC7A5 ) (Wang et al., 2011)

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Safety, Eligibility, and When to Seek Provider Guidance Unexpected weight gain or plateau on GLP-1 therapy warrants provider reassessment, not medication abandonment

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